Publications Simona Chera

2025

  1. Vašíček J, Kuznetsova KG, Skiadopoulou D, Unger L, Chera S, Ghila LM, Bandeira N, Njølstad PR, Johansson S, Bruckner S, Käll L, Vaudel M. ProHap enables human proteomic database generation accounting for population diversity. Nat Methods. 2025 Feb;22(2):273-277. doi: 10.1038/s41592-024-02506-0. Epub 2024 Dec 9. PMID: 39653819.

2024

  1. Sinturel F, Chera S, Brulhart-Meynet MC, Montoya JP, Lefai E, Jornayvaz FR, D’Angelo G, Jung MK, Pataky Z, Riezman H, Dibner C. Alterations of lipid homeostasis in morbid obese patients are partly reversed by bariatric surgery. iScience. 2024 Aug 26;27(9):110820. doi: 10.1016/j.isci.2024.110820. PMID: 39297163; PMCID: PMC11409037.
  2. Mathisen AF, Larsen U, Kavli N, Unger L, Daian LM, Vacaru AM, Vacaru AM, Herrera PL, Ghila L, Chera S. Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption. Commun Biol. 2024 Jul 9;7(1):833. doi: 10.1038/s42003-024-06527-5. PMID: 38982170; PMCID: PMC11233560.
  3. Wang C, Abadpour S, Aizenshtadt A, Dalmao-Fernandez A, Høyem M, Wilhelmsen I, Stokowiec J, Olsen PA, Krauss S, Chera S, Ghila L, Ræder H, Scholz H. Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling. Front Bioeng Biotechnol. 2024 Jun 12;12:1392575. doi: 10.3389/fbioe.2024.1392575. PMID: 38933536; PMCID: PMC11199790.
  4. Mathisen AF, Vacaru AM, Unger L, Lamba EM, Mardare OA, Daian LM, Ghila L, Vacaru AM, Chera S. Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset. Sci Rep. 2024 Jun 25;14(1):14669. doi: 10.1038/s41598-024-65454-x. PMID: 38918575; PMCID: PMC11199597.
  5. Mathisen AF, Legøy TA, Larsen U, Unger L, Abadpour S, Paulo JA, Scholz H, Ghila L, Chera S. The age-dependent regulation of pancreatic islet landscape is fueled by a HNF1a-immune signaling loop. Mech Ageing Dev. 2024 Aug;220:111951. doi: 10.1016/j.mad.2024.111951. Epub 2024 May 31. PMID: 38825059.
  6. Wang C, Abadpour S, Olsen PA, Wang D, Stokowiec J, Chera S, Ghila L, Ræder H, Krauss S, Aizenshtadt A, Scholz H. Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells. Transpl Int. 2024 Jan 18;37:11900. doi: 10.3389/ti.2024.11900. PMID: 38304198; PMCID: PMC10830798.
  7. Unger L, Mathisen AF, Chera S, Legøy TA, Ghila L. The GLI code controls HNF1A levels during foregut differentiation. Int J Dev Biol. 2024;68(4):223-230. doi: 10.1387/ijdb.230220lg. PMID: 38270262.
  8. Unger L, Ghila L, Chera S. Targeted Gene Silencing by Using GapmeRs in Differentiating Human-Induced Pluripotent Stem Cells (hiPSC) Toward Pancreatic Progenitors. Methods Mol Biol. 2024;2736:23-38. doi: 10.1007/7651_2023_498. PMID: 37615889.

2023

  1. Sinturel F, Chera S, Brulhart-Meynet MC, Montoya JP, Stenvers DJ, Bisschop PH, Kalsbeek A, Guessous I, Jornayvaz FR, Philippe J, Brown SA, D’Angelo G, Riezman H, Dibner C. Circadian organization of lipid landscape is perturbed in type 2 diabetic patients. Cell Rep Med. 2023 Dec 19;4(12):101299. doi: 10.1016/j.xcrm.2023.101299. Epub 2023 Nov 27. PMID: 38016481; PMCID: PMC10772323.
  2. Mathisen AF, Abadpour S, Legøy TA, Paulo JA, Ghila L, Scholz H, Chera S. Global proteomics reveals insulin abundance as a marker of human islet homeostasis alterations. Acta Physiol (Oxf). 2023 Oct;239(2):e14037. doi: 10.1111/apha.14037. Epub 2023 Aug 24. PMID: 37621186; PMCID: PMC10592125.
  3. Chera S, Rentzsch F. Stem cells: The cell that does it all. Curr Biol. 2023 Jun 5;33(11):R434-R436. doi: 10.1016/j.cub.2023.04.039. PMID: 37279662.
  4. Daian LM, Tanko G, Vacaru AM, Ghila L, Chera S, Vacaru AM. Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A. Int J Mol Sci. 2023 Jan 19;24(3):2023. doi: 10.3390/ijms24032023. PMID: 36768343; PMCID: PMC9916570.